Dental Treatment Approach in Two Patients with Osteogenesis Imperfecta: Case Report

Osteogenesis imperfecta (OI) is a very common, inherited autosomal dominant disease. It characterized by deformity and fragility in bone structure, blue sclera, hearing loss, scoliosis, dentinogenesis imperfecta. Molecular studies have shown that the cause of OI mutation genes named COLIA1 COLIA2 both chains collagen. Biochemical tests examine collagen structure or molecular DNA are used for making definite diagnosis reported prevalence between 1: 5000 20000 newborns, regardless ethnic racial discrimination. In addition to hard tissue involvement, tissues commonly contain such as tendons, ligaments, skin, dental tissue, middle inner ear may be affected. Common anomalies patients (DI) malocclusion. this case report, two male patients, 18 19 years old, changes mouth, teeth body were examined. The treatment was completed applying resin-based composite restorations affected with minimally invasive approach.